Baclof 10 Tablet for Muscle Spasms & Spasticity

Product Introduction

Baclof 10 Tablet contains baclofen, a powerful muscle relaxant that has transformed the management of spasticity and muscle rigidity associated with various neurological conditions. This medication works directly on the central nervous system to provide relief from painful muscle spasms and improve mobility for patients with challenging neuromuscular disorders.

Baclofen, the active ingredient in Baclof 10, is a gamma-aminobutyric acid (GABA) derivative that primarily acts as a GABA-B receptor agonist in the spinal cord. By mimicking the inhibitory neurotransmitter GABA, baclofen helps reduce the excessive signals that cause muscle stiffness and spasms. This unique mechanism makes it particularly effective for conditions where muscle hyperactivity significantly impacts quality of life.

Patients with multiple sclerosis, spinal cord injuries, or other neurological disorders often experience debilitating muscle spasticity that limits movement and causes considerable pain. Baclof 10 provides these patients with much-needed relief, improving functional capacity and enhancing daily activities. The medication doesn't cure the underlying condition but offers symptomatic management that can dramatically improve patient comfort and functionality.

The 10mg strength of Baclof is typically the starting dose for most patients, allowing physicians to carefully titrate the medication based on individual response and tolerability. This gradual approach helps minimize side effects while maximizing therapeutic benefits. The oral tablet formulation provides convenient administration for long-term management of chronic spasticity conditions.

Healthcare providers value Baclof 10 for its established efficacy profile and predictable response patterns. When properly prescribed and monitored, this medication offers a balance between spasticity reduction and preservation of necessary muscle tone for functional activities. The dosage can be adjusted over time to maintain optimal benefit as the patient's condition evolves.

Despite its benefits, Baclof requires careful administration and monitoring. Abrupt discontinuation can lead to serious withdrawal symptoms, and dose adjustments must be made gradually. When used appropriately under medical supervision, Baclof 10 remains an essential tool in the comprehensive management of muscle spasticity, offering patients improved comfort, mobility, and quality of life.

💪 Baclof 10 Tablet – Get relief from muscle stiffness and spasms.

Baclof 10 Tablet

💊 Type: Prescription Medicine

🏢 Manufacturer: Intas Pharmaceuticals Ltd

🧪 Composition: Baclofen (10mg)

🌡️ Storage: Store below 30°C in a cool, dry place

🔁 Similar Medicines: [Click here to view substitutes]

Key Composition & Ingredients

Active Ingredient: Baclofen 10mg
Inactive Ingredients: Microcrystalline cellulose, lactose monohydrate, pregelatinized starch, colloidal silicon dioxide, magnesium stearate, and other pharmaceutical excipients

Uses of Baclof Tablet

Treatment of muscle spasticity associated with multiple sclerosis
Relief from spinal cord injuries or diseases that cause muscle rigidity
Management of spasticity in cerebral palsy
Treatment of muscle spasms in certain types of stroke patients
Management of painful muscle spasms in various neurological disorders
Adjunctive therapy for trigeminal neuralgia
Relief from muscle rigidity in certain cases of Parkinson's disease
Management of muscle spasms associated with tetanus

Benefits of Baclof Tablet

Reduces painful muscle spasms and cramping
Improves mobility and range of motion
Enhances ability to perform daily activities
Decreases muscle stiffness and rigidity
Improves sleep by reducing nighttime muscle spasms
Reduces pain associated with muscle hypertonicity
May help delay the need for surgical interventions
Allows for better participation in physical therapy
Improves overall quality of life for patients with spasticity

How Baclof Tablet Works (Mechanism of Action)

Baclofen, the active ingredient in Baclof 10 tablet, works through the following mechanisms:

Binds primarily to GABA-B receptors in the spinal cord
Mimics the action of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter
Decreases the release of excitatory neurotransmitters (glutamate and aspartate) from presynaptic terminals
Reduces calcium influx into nerve terminals
Inhibits monosynaptic and polysynaptic reflexes at the spinal level
Decreases transmission of impulses from spinal afferent to motor neurons
Results in decreased muscle tone and reduced frequency and intensity of muscle spasms
Provides relief without affecting consciousness or voluntary muscle control

This mechanism allows Baclof to target muscle spasticity while preserving voluntary muscle function when used at appropriate dosages.

Dosage of Baclof Tablet

Daily Dose

Initial dose: Usually 5mg (half tablet) three times daily
Titration: Gradually increase by 5mg every 3 days
Maintenance dose: Typically 10mg three times daily (30mg/day)
Maximum dose: Up to 80mg daily in severe cases (divided doses)
Elderly patients: Start with lower doses and increase gradually

Missed Dose

Take as soon as remembered if within a few hours
Skip the missed dose if it's almost time for the next scheduled dose
Never take double doses to make up for missed ones
Contact healthcare provider if multiple doses are missed

Overdose

Seek immediate medical attention
Symptoms may include severe drowsiness, vomiting, muscle weakness, seizures, respiratory depression, or coma
Treatment may include gastric lavage, activated charcoal, and supportive measures

How to Use Baclof Tablet

Take exactly as prescribed by your healthcare provider
Take with food or milk to minimize stomach upset
Swallow tablets whole with a full glass of water
Use at evenly spaced intervals throughout the day
Take at the same times each day to maintain blood levels
Do not crush, chew, or break the tablets unless specifically instructed
Never stop taking abruptly; gradual dose reduction is essential
Follow complete course of treatment even if symptoms improve

Side Effects of Baclof Tablet

Common Side Effects

Drowsiness or fatigue
Dizziness or lightheadedness
Weakness
Headache
Nausea
Constipation or diarrhea
Increased urination
Insomnia

Serious Side Effects (Require Immediate Medical Attention)

Severe mood changes or depression
Hallucinations or confusion
Irregular heartbeat
Chest pain
Difficulty breathing
Seizures
Severe allergic reactions (rash, itching, swelling)
Unusual bleeding or bruising

How to Manage Side Effects

For drowsiness: Avoid driving or operating machinery until tolerance develops
For nausea: Take medication with food
For dizziness: Change positions slowly; avoid sudden movements
For headache: Use appropriate pain relievers as recommended by doctor
For dry mouth: Sip water frequently, use sugar-free candies or gum
Report persistent or severe side effects to your healthcare provider

Safety Advice for Baclof Tablet

Alcohol

UNSAFE: Alcohol may increase drowsiness and dizziness; avoid completely

Pregnancy

CONSULT DOCTOR: Use only if clearly needed; potential risks to the fetus must be discussed

Breastfeeding

CAUTION: Baclofen passes into breast milk; discuss with your doctor before use

Driving

UNSAFE: May cause drowsiness, dizziness, and blurred vision; avoid driving initially

Kidney

CAUTION: Lower doses may be needed; careful monitoring required for kidney impairment

Liver

CAUTION: May require dose adjustment; monitor liver function periodically

Children

CONSULT DOCTOR: Safety and efficacy in children under 12 not fully established

Older Patients

CAUTION: Start with lower doses; more susceptible to side effects like confusion

Allergy

AVOID: Do not use if allergic to baclofen or any ingredients in Baclof 10

Warnings & Precautions for Baclof Tablet

Never discontinue abruptly; gradual tapering is essential to prevent withdrawal
Use with caution in patients with epilepsy as it may lower seizure threshold
Monitor patients with psychiatric disorders for mood changes or depression
Use cautiously in patients with respiratory disorders
Special care needed for patients with impaired kidney function
May worsen symptoms in Parkinson's disease patients
Use with caution in patients with diabetes as it may affect blood sugar levels
Monitor for increased intracranial pressure in patients with cerebrovascular disorders
Use cautiously in patients with peptic ulcer disease
Regular monitoring recommended for patients with hypertension or cardiac conditions

Interactions with Baclof Tablet

Drug-Drug Interactions

CNS depressants (opioids, benzodiazepines, alcohol): Enhanced sedative effects
Antihypertensive medications: May enhance hypotensive effects
Tricyclic antidepressants: May increase muscle relaxant effects
MAO inhibitors: May increase CNS depression
Levodopa: May worsen Parkinson's symptoms
Lithium: May enhance hyperkinesia
Antidiabetic drugs: May affect blood glucose control
NSAIDs: May increase risk of side effects when used together

Drug-Food Interactions

High-fat meals may slightly delay absorption but do not affect overall bioavailability
No significant interactions with specific foods have been reported

Contraindications of Baclof Tablet

Hypersensitivity to baclofen or any component of the formulation
Active peptic ulcer disease
Severe psychiatric disorders
Severe respiratory insufficiency
Severe hepatic impairment
Patients with certain rare hereditary problems of galactose intolerance
Parkinson's disease (relative contraindication - use with caution)

Diet & Lifestyle Advice

Maintain regular physical therapy exercises as recommended by healthcare provider
Practice proper posture and body mechanics to complement medication effects
Engage in gentle stretching exercises to maintain muscle flexibility
Ensure adequate hydration throughout the day
Implement stress reduction techniques as stress can worsen muscle spasticity
Maintain consistent sleep schedule to maximize medication benefits
Use assistive devices as recommended by physical therapists
Consider complementary therapies like massage or warm baths to enhance relief
Avoid caffeine consumption, which may worsen muscle tension

Why Doctors Recommend This Medicine

Doctors prescribe Baclof 10 because:

It effectively reduces muscle spasticity in various neurological conditions
It has a well-established safety profile when used appropriately
It improves patient comfort and functionality
It enhances the effectiveness of physical therapy interventions
It can be titrated to find the optimal balance between spasticity reduction and side effects
It preserves voluntary muscle function when dosed properly
It addresses both painful spasms and chronic muscle rigidity
It has demonstrated long-term efficacy in appropriate patients

Substitutes of Baclof Tablet & Alternative Medicines

Tizanidine (Zanaflex) - Alpha-2 adrenergic agonist with shorter duration of action
Diazepam (Valium) - Benzodiazepine with muscle relaxant properties
Dantrolene (Dantrium) - Acts directly on skeletal muscle
Cyclobenzaprine (Flexeril) - For short-term relief of muscle spasms
Intrathecal baclofen pump - For severe cases not responding to oral therapy
Botulinum toxin injections - For localized spasticity
Physical therapy techniques - Non-pharmacological management
Orthotic devices - For positioning and preventing contractures

Storage Guidelines

Store at room temperature between 68°F to 77°F (20°C to 25°C)
Protect from light and moisture
Keep in the original container with the lid tightly closed
Store away from heat and direct sunlight
Keep out of reach of children and pets
Do not store in the bathroom or kitchen where humidity is high
Do not use after the expiration date printed on the package
Dispose of unused medication properly as directed by healthcare provider

Quick Tips for Baclof Tablet

Never stop taking this medication abruptly
Maintain regular dosing schedule for consistent relief
Allow 2-3 weeks for full therapeutic effect to develop
Keep a symptom diary to help your doctor optimize dosage
Stand up slowly to minimize dizziness
Consider taking with food to reduce stomach upset
Avoid activities requiring alertness until you know how the medication affects you
Stay well-hydrated while taking this medication
Inform all healthcare providers that you're taking baclofen
Wear medical identification indicating you take baclofen

Fact Box

Chemical Class: Gamma-aminobutyric acid (GABA) derivative
Habit Forming: Low potential but may cause physical dependence with long-term use
Therapeutic Class: Skeletal muscle relaxant
Action Class: GABA-B receptor agonist

Useful Diagnostic Tests

Muscle tone assessment (Ashworth scale)
Reflex testing
Range of motion measurements
Kidney function tests (prior to and during treatment)
Liver function tests (periodically)
Electroencephalogram (EEG) for patients with history of seizures
Urodynamic testing (for patients with bladder symptoms)

More Information & References

For additional information about Baclof 10, consult:

Your healthcare provider or pharmacist
National Multiple Sclerosis Society guidelines
American Academy of Neurology recommendations
Package insert and medication guide
Physical medicine and rehabilitation resources

Disclaimer

This information is intended for educational purposes only and does not replace professional medical advice. Always consult with your healthcare provider regarding any medical conditions and before starting, stopping, or changing any medication regimen. Individual results may vary, and all potential risks and benefits should be discussed with your healthcare provider. This medication should only be used under proper medical supervision.