Bio-D3 Strong Soft Gelatin Capsule
Prescription Required
Marketer
Macleods Pharmaceuticals Pvt Ltd
SALT COMPOSITION
Calcitriol (0.25mcg) + Calcium Carbonate (1250mg) + Zinc (7.5mg) + Magnesium (50mg) + Vitamin K2-7 (45mcg) + Methylcobalamin (1500mcg) + L-Methyl Folate (800mcg)
Storage
Store below 25°C
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Product Introduction
Bio-D3 Strong Soft Gelatin Capsule is a comprehensive nutritional supplement formulated to address multiple micronutrient deficiencies with a single daily dose. This advanced formulation combines seven essential nutrients that work synergistically to support bone health, immune function, cardiovascular health, and neurological well-being.
The cornerstone of this supplement is its unique combination of bone-supporting nutrients. Calcitriol, the active form of Vitamin D3, works in conjunction with Calcium Carbonate to enhance calcium absorption and utilization, while Vitamin K2-7 ensures proper calcium deposition in bones rather than soft tissues. This trio creates an optimal environment for bone mineralization and strength.
Beyond bone health, Bio-D3 Strong addresses critical nutritional needs with its inclusion of Zinc for immune support, Magnesium for muscle and nervous system function, Methylcobalamin (Vitamin B12) for neurological health, and L-Methylfolate for cellular metabolism and homocysteine regulation. These bioactive forms of vitamins ensure superior absorption and utilization compared to standard supplements.
The soft gelatin capsule delivery system enhances the bioavailability of these nutrients, particularly the fat-soluble components like Vitamin K2-7 and Calcitriol. This advanced delivery method protects sensitive nutrients from degradation while facilitating optimal absorption in the digestive tract.
Bio-D3 Strong is particularly beneficial for individuals with increased nutritional demands, including the elderly, postmenopausal women, those with limited sun exposure, individuals with malabsorption issues, vegans/vegetarians, and patients recovering from prolonged illness. The careful balance of nutrients helps address multiple deficiency states simultaneously while minimizing the pill burden associated with taking individual supplements.
As with any nutritional supplement, Bio-D3 Strong is designed to complement, not replace, a balanced diet. Its comprehensive formulation represents an evidence-based approach to nutritional support for those seeking to maintain optimal health or address specific deficiency-related concerns.
Key Composition & Ingredients
- Calcitriol (0.25mcg): The biologically active form of Vitamin D3, which enhances calcium absorption and regulates calcium homeostasis
- Calcium Carbonate (1250mg): Provides elemental calcium necessary for bone mineralization, muscle contraction, and nerve function
- Zinc (7.5mg): Essential trace mineral supporting immune function, protein synthesis, wound healing, and DNA synthesis
- Magnesium (50mg): Critical mineral for over 300 enzymatic reactions, including energy production, muscle function, and nervous system regulation
- Vitamin K2-7 (45mcg): Directs calcium to bones rather than soft tissues and activates proteins involved in bone metabolism
- Methylcobalamin (1500mcg): Active form of Vitamin B12 essential for nerve function, DNA synthesis, and red blood cell formation
- L-Methylfolate (800mcg): Biologically active form of folate that bypasses genetic variations in folate metabolism pathways
Uses of Bio-D3 Strong Soft Gelatin Capsule
- Prevention and treatment of vitamin D and calcium deficiency
- Support for bone health and osteoporosis prevention
- Adjunctive therapy in osteoporosis management
- Nutritional support during pregnancy and lactation (under medical supervision)
- Management of vitamin B12 and folate deficiencies
- Support for individuals with limited sun exposure
- Nutritional supplementation for elderly individuals
- Support for individuals with malabsorption conditions
- Maintenance of immune system health
- Nutritional support for vegans and vegetarians
Benefits of Bio-D3 Strong Soft Gelatin Capsule
- Comprehensive support for bone health and mineralization
- Enhanced calcium absorption and utilization
- Improved nerve and muscle function
- Support for cardiovascular health through proper calcium distribution
- Reduction in homocysteine levels through methylated B vitamins
- Support for cognitive function and neurological health
- Enhanced immune system function
- Improved energy production at cellular level
- Reduced risk of multiple nutrient deficiencies
- Convenient single-capsule dosing for enhanced compliance
How Bio-D3 Strong Soft Gelatin Capsule Works
This multi-nutrient supplement functions through several complementary mechanisms:
- Calcitriol (0.25mcg): As the active form of Vitamin D3, it enhances intestinal absorption of calcium and phosphorus, stimulates calcium reabsorption in kidneys, and regulates bone remodeling by interacting with vitamin D receptors in bone cells.
- Calcium Carbonate (1250mg): Provides bioavailable calcium necessary for bone formation, muscular contraction, nerve transmission, and cellular signaling pathways. The carbonate form offers a high elemental calcium content.
- Vitamin K2-7 (45mcg): Activates osteocalcin, a protein that binds calcium to the bone matrix, and inhibits calcification of blood vessels and soft tissues by activating matrix Gla protein (MGP).
- Zinc (7.5mg): Functions as a cofactor for numerous enzymes involved in immune function, protein synthesis, wound healing, DNA synthesis, and cell division. It also has antioxidant properties.
- Magnesium (50mg): Works as a cofactor in over 300 enzymatic reactions, regulates calcium transport, supports energy production through ATP synthesis, and modulates neuromuscular transmission.
- Methylcobalamin (1500mcg): Functions as a cofactor in DNA synthesis, supports myelin formation for nerve health, and participates in the conversion of homocysteine to methionine via methionine synthase.
- L-Methylfolate (800mcg): Participates in DNA synthesis and repair, supports red blood cell formation, and works with methylcobalamin in homocysteine metabolism, bypassing genetic variations in the MTHFR enzyme.
Dosage of Bio-D3 Strong Soft Gelatin Capsule
Daily Dose
- Adults: One capsule daily with meals or as directed by healthcare provider
- Elderly: One capsule daily, preferably with breakfast or lunch
- Pregnant/Lactating Women: Use only under medical supervision
Missed Dose
- Take as soon as remembered if within the same day
- Skip the missed dose if remembered the next day
- Do not double dose to make up for a missed dose
Overdose
- Symptoms may include nausea, vomiting, constipation, lethargy, confusion
- Long-term overdose may lead to hypercalcemia, kidney stones, or tissue calcification
- Seek immediate medical attention if overdose is suspected
How to Use Bio-D3 Strong Soft Gelatin Capsule
- Take one capsule daily with water
- Best absorbed when taken with a meal containing some fat
- Preferably take in the morning or afternoon rather than evening
- Swallow the capsule whole; do not break, crush, or chew
- Store at room temperature away from moisture and light
- Maintain consistent daily dosing for optimal results
Side Effects of Bio-D3 Strong Soft Gelatin Capsule
Common Side Effects
- Mild gastric discomfort
- Constipation
- Nausea
- Metallic taste
Serious Side Effects
- Hypercalcemia (excessive calcium in blood)
- Kidney stones
- Allergic reactions
- Heart rhythm irregularities (rare)
- Vitamin K-anticoagulant interactions
Safety Advice for Bio-D3 Strong Soft Gelatin Capsule
Alcohol
- No known significant interaction, but alcohol may interfere with nutrient absorption
Pregnancy
- Use only under medical supervision
- Beneficial for fetal development when prescribed appropriately
Breastfeeding
- Generally considered safe, but consult healthcare provider
- Supports maternal and infant nutritional needs
Driving
- No known effects on ability to drive or operate machinery
Kidney Function
- Use with caution in patients with kidney disease
- May require dose adjustment or monitoring of calcium levels
Liver Function
- Generally safe for patients with liver conditions
- No specific dose adjustments required for mild to moderate liver impairment
Children
- Not recommended for children; pediatric formulations available
Older Patients
- Particularly beneficial, but may require monitoring for calcium levels
- May need adjusted dosing based on kidney function
Allergy
- Avoid if allergic to any component of the formulation
- Soft gelatin capsule may contain gelatin (animal origin)
Warnings & Precautions
- Regular monitoring recommended for long-term use
- Not suitable for patients with hypercalcemia
- Use with caution in sarcoidosis, hyperparathyroidism, and kidney stones
- May interact with certain medications (see interactions)
- Not a substitute for a balanced diet
- Exceeding recommended dose may cause adverse effects
- Consult healthcare provider before use if taking multiple medications
- Not recommended for patients with malignancies affecting bone tissue
- Vitamin K component may affect anticoagulant therapy
Interactions with Bio-D3 Strong Soft Gelatin Capsule
Drug-Drug Interactions
- Anticoagulants (Warfarin): Vitamin K2 may reduce effectiveness
- Thiazide Diuretics: May increase risk of hypercalcemia
- Bisphosphonates: Calcium may reduce absorption if taken simultaneously
- Levothyroxine: Calcium may interfere with absorption
- Tetracycline Antibiotics: Calcium may reduce antibiotic effectiveness
- Fluoroquinolone Antibiotics: Calcium, magnesium, and zinc may reduce absorption
- Anticonvulsants: May affect vitamin D metabolism
- Glucocorticoids: May reduce calcium absorption
- Metformin: May reduce B12 absorption over time
Drug-Food Interactions
- High oxalate foods (spinach, rhubarb) may reduce calcium absorption
- High phytate foods may reduce zinc and magnesium absorption
- Fat-soluble components (vitamins D and K) better absorbed with fat-containing meals
Contraindications
- Hypercalcemia
- Advanced kidney disease without medical supervision
- Hypervitaminosis D
- Known allergy to any ingredients
- Patients with calcium-containing kidney stones (relative contraindication)
- Severe hyperparathyroidism
- Patients with malignancies affecting bone metabolism
Diet & Lifestyle Advice
- Maintain adequate hydration (8-10 glasses of water daily)
- Include calcium-rich foods in diet (dairy, leafy greens, fortified foods)
- Regular weight-bearing exercise for bone health
- Ensure adequate but safe sun exposure for natural vitamin D production
- Limit caffeine and alcohol consumption
- Avoid smoking
- Consider evaluation for osteoporosis if at risk
- Balanced diet rich in fruits, vegetables, and whole grains
- Periodic bone density testing for those at risk for osteoporosis
Why Doctors Recommend This Medicine
Physicians recommend Bio-D3 Strong Soft Gelatin Capsule for:
- Patients with multiple nutrient deficiencies
- Individuals with increased calcium and vitamin D requirements
- Postmenopausal women at risk for osteoporosis
- Elderly patients with poor nutritional status
- Those with limited sun exposure
- Patients with malabsorption conditions
- Individuals with MTHFR genetic variations affecting folate metabolism
- Vegans and vegetarians at risk for B12 deficiency
- Patients requiring bone health support beyond calcium alone
Substitutes & Alternative Medicines
Pharmaceutical Alternatives
- Separate calcium and vitamin D supplements
- Calcitriol standalone formulations
- Calcium with vitamin D combinations
- B-complex vitamins with methylated forms
- Magnesium and zinc individual supplements
Natural Alternatives
- Increased dietary sources of calcium (dairy, fortified plant milks)
- Sun exposure for vitamin D (15-30 minutes daily on exposed skin)
- Leafy greens and nuts for magnesium
- Seafood, seeds, and legumes for zinc
- Fermented foods for vitamin K2
- Note: Natural alternatives may not provide therapeutic doses for deficiency states
Storage Guidelines
- Store at room temperature between 59-86°F (15-30°C)
- Keep away from direct sunlight and heat
- Protect from moisture
- Keep container tightly closed
- Store in original packaging
- Keep out of reach of children
- Do not use after expiration date
User Feedback & Patient Concerns
Common patient feedback includes:
- Reports of improved energy levels
- Questions about timing of doses with other medications
- Concerns about potential interactions with prescription drugs
- Feedback about improved nail and hair quality
- Questions about duration of therapy
- Reports of constipation when initiating therapy
- Interest in bone density improvements over time
Quick Tips
- Take with the largest meal of the day for better absorption
- Space at least 2 hours apart from antibiotics or thyroid medications
- Stay consistent with daily dosing for optimal results
- Report unusual symptoms to healthcare provider
- Maintain adequate hydration to prevent constipation
- Consider periodic blood tests to monitor calcium and vitamin D levels
- If you take anticoagulants, consult your doctor before starting
- Combine with weight-bearing exercise for optimal bone health
Fact Box
- Chemical Class: Multi-nutrient supplement
- Habit Forming: No
- Therapeutic Class: Bone health supplement, Nutritional supplement
- Action Class: Vitamin-mineral combination
Useful Diagnostic Tests
- Serum 25-hydroxyvitamin D levels
- Serum calcium and phosphorus
- Bone mineral density test (DEXA scan)
- Serum magnesium levels
- Complete blood count
- Homocysteine levels
- Serum B12 levels
- Kidney function tests
Disclaimer
This information is provided for educational purposes only and does not replace professional medical advice. Consult your healthcare provider before starting any supplement, especially if you have underlying health conditions or take medications. Individual responses may vary. The product is not intended to diagnose, treat, cure, or prevent any disease.
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