Ivabrad 5mg Tablet
Prescription Required
Marketer
Lupin Ltd
SALT COMPOSITION
Ivabradine (5mg)
Storage
Store below 30°C
Click here to view all substitutes
Product Introduction: Ivabrad 5mg is a prescription medication containing Ivabradine (5mg), primarily used for managing chronic stable angina and heart failure. It works by selectively inhibiting the If (funny) current in the sinoatrial node, reducing heart rate without affecting myocardial contractility. Unlike beta-blockers, Ivabradine is selective in its action, making it suitable for patients intolerant to beta-blockers or requiring additional heart rate control.
This medication is essential for improving exercise capacity and reducing hospitalization risks in heart failure patients. It is often prescribed alongside standard heart failure treatments like beta-blockers, ACE inhibitors, and diuretics to achieve optimal heart function. Patients prescribed Ivabradine must adhere to dosage instructions carefully and consult their doctor for any concerns regarding side effects or interactions.
Ivabradine is particularly useful for patients with chronic heart conditions who require long-term management of symptoms. It helps in reducing the workload on the heart, thereby improving overall cardiac function. Regular check-ups and continuous monitoring of heart rate and blood pressure are recommended for patients taking this medication to ensure optimal benefits and minimize any potential risks.
Key Composition & Ingredients:
- Active Ingredient: Ivabradine (5mg)
- Excipients: Microcrystalline cellulose, Lactose monohydrate, Magnesium stearate, and Film coating agents.
These excipients play a crucial role in ensuring the stability and effectiveness of the medication, helping it to be properly absorbed in the body and exert its therapeutic effects efficiently.
Uses of Ivabrad 5mg Tablet:
- Management of chronic stable angina pectoris in patients with normal sinus rhythm.
- Treatment of chronic heart failure (NYHA Class II-IV) with reduced ejection fraction.
- Helps reduce the risk of hospitalization due to worsening heart failure.
- Used in patients who cannot tolerate beta-blockers or require additional heart rate control.
- Helps in improving symptom control and overall quality of life in heart failure patients.
Benefits of Ivabrad 5mg Tablet:
- Effectively reduces heart rate without lowering blood pressure.
- Helps improve exercise tolerance in patients with angina.
- Reduces heart failure-related hospitalizations.
- Provides an alternative to beta-blockers in patients with contraindications.
- Enhances oxygen supply to the heart muscle, reducing angina symptoms.
- Helps maintain a stable heart rhythm, preventing unnecessary stress on the heart.
How Ivabrad 5mg Tablet Works: Ivabradine works by inhibiting the If current (funny current) in the sinoatrial node, which is responsible for pacemaker activity in the heart. By reducing the heart rate, Ivabradine lowers myocardial oxygen demand, improving angina symptoms and heart failure outcomes.
Unlike other heart medications that affect multiple parameters such as blood pressure and contractility, Ivabradine specifically targets heart rate, making it a precise and effective treatment for heart failure and angina patients who need heart rate regulation without affecting other cardiac functions.
Mechanism of Action: Ivabradine selectively inhibits the hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in the sinoatrial node. This leads to a reduction in pacemaker activity and slows down the heart rate without affecting contractility or blood pressure.
By reducing heart rate, Ivabradine decreases the heart's oxygen demand, allowing it to function more efficiently even in patients with reduced heart function due to heart failure.
Dosage of Ivabrad 5mg Tablet:
- Recommended Daily Dose: Usually 5mg twice daily, adjustable based on heart rate response.
- Missed Dose: Take as soon as remembered unless close to the next dose.
- Overdose: Symptoms include bradycardia (slow heart rate), dizziness, and fatigue. Seek immediate medical attention.
A healthcare provider will determine the appropriate dosage based on the patient’s condition, ensuring maximum benefit while minimizing potential side effects.
Mode of Action: Unlike beta-blockers, Ivabradine acts only on the pacemaker cells, preventing excessive heart rate reduction and maintaining myocardial contractility.
This targeted action makes it safer for patients who cannot tolerate beta-blockers or require a more specific approach to heart rate control.
How to Use Ivabrad 5mg Tablet:
- Take orally with water, preferably with meals.
- Do not crush or chew.
- Follow the prescribed dosage strictly.
Directions for Use:
- Take twice daily, or as directed by a physician.
- Regular monitoring of heart rate and ECG is recommended.
- Avoid grapefruit juice as it may affect drug metabolism.
Side Effects of Ivabrad 5mg Tablet:
- Common: Bradycardia, dizziness, blurred vision.
- Serious: Atrial fibrillation, severe hypotension.
- Rare: Skin rash, liver enzyme elevation.
- Other potential side effects: Fatigue, nausea, headache, and irregular heartbeat.
Side Effects & How to Manage Them:
- Bradycardia: Consult a doctor if heart rate drops significantly.
- Dizziness: Avoid sudden posture changes.
- Blurred Vision: Usually temporary, seek medical advice if persistent.
- Fatigue: Ensure adequate rest and hydration.
Safety Advices:
- Avoid in patients with severe liver impairment.
- Monitor patients with low heart rates or pacemakers.
- Not recommended for pregnant or breastfeeding women without medical consultation.
- Regular heart rate monitoring is essential to prevent complications.
Diet & Lifestyle Advice:
- Follow a heart-healthy diet rich in omega-3 and fiber.
- Regular exercise to maintain cardiovascular health.
- Avoid high caffeine intake, which may increase heart rate.
- Maintain a balanced diet to support overall heart function.
- Manage stress through meditation and relaxation techniques.
- Avoid smoking and excessive alcohol consumption as they can worsen heart conditions.
Why Doctors Recommend This Medicine?
- Selectively lowers heart rate without affecting blood pressure or contractility.
- Beneficial for angina and heart failure management.
- Improves quality of life and reduces hospitalization risks.
Substitutes & Alternative Medicines:
- Ivabid 5mg
- Bradia 5mg
- Coralan 5mg
Alternative Medicines
- GLYCINORM M 80MG STRIP OF 15 TABLETS
- GLIZID M STRIP OF 15 TABLETS
- GLYKIND M STRIP OF 10 TABLETS
- GLYCINORM M OD 60MG STRIP OF 10 TABLETS
Other Products from this Brand
- IVABRAD OD 10MG STRIP OF 10 TABLETS
- IVABRAD 7.5MG STRIP OF 15 TABLETS
- IVABRAD OD 15MG STRIP OF 10 TABLETS
- IVABRAD 7.5MG TABLET
- IVABRAD 10MG STRIP OF 10 TABLETS
Storage Guidelines:
- Store at room temperature (15-30°C)
- Keep away from moisture and heat
- Keep out of children’s reach
User Feedback & Patient Concerns:
- Most users report effective heart rate control.
- Some experience mild dizziness in initial days.
- Patients appreciate its targeted action and better tolerance compared to beta-blockers.
Quick Tips:
- Take with food to enhance absorption.
- Do not suddenly stop medication without consulting a doctor.
- Regularly monitor heart rate and blood pressure.
- Report any irregular heartbeat or vision disturbances to a doctor immediately.
Fact Box:
- Chemical Class: Benzazepine derivative
- Habit Forming: No
- Therapeutic Class: Cardiovascular
- Action Class: Hyperpolarization-activated cyclic nucleotide-gated channel blocker
Useful Diagnostic Tests:
- ECG Monitoring
- Heart Rate Analysis
- Liver Function Test (if needed)
More Information & References: For more details, consult official medical sources or discuss with a cardiologist.
https://cdscoonline.gov.in/CDSCO/Drugs
https://www.torrentian.com/pisheet/Upload/PI_Sheet/2306.pdf
Disclaimer
THE CONTENTS OF THIS WEBSITE ARE FOR INFORMATIONAL PURPOSES ONLY AND ARE NOT INTENDED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE, DIAGNOSIS, TREATMENT, OR PREVENTION OF A DISEASE OR MEDICAL CONDITION. PLEASE CONSULT A PHYSICIAN FOR THE TREATMENT AND/OR MANAGEMENT OF ANY DISEASE OR MEDICAL CONDITION WITHOUT DELAY.