
Oxra 10mg Tablet
Prescription Required
Marketer
Sun Pharmaceutical Industries Ltd
SALT COMPOSITION
Dapagliflozin (10mg)
Storage
Store below 30°C
Click here to view all substitutes
Product Introduction
Oxra 10mg Tablet contains Dapagliflozin (10mg) and belongs to the class of sodium-glucose co-transporter-2 (SGLT2) inhibitors. This medication is primarily used for managing type 2 diabetes mellitus by helping the kidneys remove excess glucose from the body through urine. It effectively lowers blood sugar levels, reduces the risk of cardiovascular diseases, and aids in weight loss in diabetic patients.
Dapagliflozin is prescribed as monotherapy or in combination with other antidiabetic medications such as metformin or insulin. It helps improve glycemic control in adults by inhibiting glucose reabsorption in the kidneys, leading to increased glucose excretion. Additionally, it provides cardiovascular and renal protection, reducing the risk of heart failure and chronic kidney disease progression.
Oxra 10mg Tablet is typically taken once daily, with or without food. It is crucial to follow medical advice regarding its use, as improper dosage or discontinuation can impact blood sugar control. Patients with kidney disease, dehydration risks, or those on diuretics should take extra precautions. Regular monitoring of blood glucose levels and periodic kidney function tests are recommended for patients using this medication.
Key Composition & Ingredients
- Dapagliflozin (10mg) – The active ingredient that works by inhibiting the SGLT2 enzyme in the kidneys, reducing glucose reabsorption.
- Excipients – Include microcrystalline cellulose, lactose monohydrate, and magnesium stearate, which help in tablet formulation and absorption.
Uses of Oxra 10mg Tablet
- Type 2 Diabetes Mellitus (T2DM) – Lowers blood sugar levels by promoting glucose excretion through urine.
- Cardiovascular Protection – Reduces the risk of heart failure and related complications in diabetic patients.
- Chronic Kidney Disease (CKD) Management – Slows disease progression by reducing stress on the kidneys.
- Weight Loss Aid – Helps in reducing body weight by excreting excess glucose and calories.
Benefits of Oxra 10mg Tablet
- Helps maintain optimal blood sugar levels.
- Reduces the risk of cardiovascular complications.
- Aids in weight loss and blood pressure control.
- Provides renal protection in diabetic patients.
- Lowers the dependency on insulin or other glucose-lowering drugs.
How Oxra 10mg Tablet Works
Dapagliflozin inhibits SGLT2, a protein responsible for reabsorbing glucose in the kidneys. By blocking this process, it increases glucose excretion through urine, reducing blood sugar levels effectively.
How the Drug Works (Mechanism of Action)
Dapagliflozin acts by selectively inhibiting SGLT2 transporters in the proximal renal tubules. This mechanism reduces glucose reabsorption and promotes glucose elimination, thereby lowering plasma glucose levels independently of insulin action.
Dosage of Oxra 10mg Tablet
- Daily Dose: 10mg once daily, with or without food.
- Missed Dose: Take as soon as remembered but do not double dose.
- Overdose: May cause dehydration, dizziness, or hypoglycemia. Seek immediate medical help.
Mode of Action of Oxra 10mg Tablet
By blocking SGLT2 in the kidneys, dapagliflozin increases urinary glucose excretion, reducing both fasting and postprandial blood glucose levels without affecting insulin secretion.
How to Use Oxra 10mg Tablet
Swallow the tablet whole with water, once daily at the same time each day, with or without meals.
Directions for Use
- Follow the doctor’s prescribed dose.
- Do not crush, break, or chew the tablet.
- Maintain hydration while on this medication.
Side Effects of Oxra 10mg Tablet
- Frequent urination
- Dehydration
- Urinary tract infections (UTI)
- Increased thirst
- Low blood pressure (hypotension)
Side Effects & How to Manage Them
- Mild Symptoms: Stay hydrated to avoid dehydration.
- Severe Reactions: Seek medical help for signs of severe infections or dizziness.
Safety Advices of Oxra 10mg Tablet
- Avoid alcohol to prevent excessive blood sugar fluctuations.
- Pregnancy & Breastfeeding: Not recommended unless prescribed by a doctor.
- Kidney & Liver Conditions: Requires dose adjustment or alternative medication.
Warnings & Precautions of Oxra 10mg Tablet
- Avoid use in type 1 diabetes and diabetic ketoacidosis.
- Watch for signs of dehydration and UTIs.
Interactions with Oxra 10mg Tablet
- Drug-Drug: Can interact with diuretics, insulin, and blood pressure medications.
- Drug-Food: No significant food interactions; maintain a balanced diet.
Contraindications of Oxra 10mg Tablet
- Severe kidney disease or dialysis patients.
- Type 1 diabetes and diabetic ketoacidosis.
Safety Measures & FDA Pregnancy Category
- Category C – Use only if clearly needed under medical supervision.
Diet & Lifestyle Advice for Oxra 10mg Tablet
- Follow a low-carb, high-fiber diet.
- Stay hydrated to prevent dehydration.
- Maintain regular exercise to enhance glucose control.
- Monitor blood sugar levels regularly.
Why Doctors Recommend This Medicine?
Doctors prescribe Oxra 10mg for its dual benefits in blood sugar control and cardiovascular protection, along with kidney function support.
Substitutes of Oxra 10mg Tablet & Alternative Medicines
- Forxiga 10mg
- Dapanta 10mg
- Dapaflo 10mg
Alternative Medicines
- VISTARAX 10MG STRIP OF 10 TABLETS
- PRUGO 10MG STRIP OF 15 TABLETS
- PRUGO 25MG STRIP OF 15 TABLETS
- HICOPE BOTTLE OF 15ML DROPS
Other Products from this Brand
- OXRA S 10/100MG STRIP OF 15 TABLETS
- OXRA 5MG STRIP OF 14 TABLETS
- OXRA S 5/50MG STRIP OF 15 TABLETS
- OXRA S 10/50MG STRIP OF 15 TABLETS
- OXRA S 5/100MG STRIP OF 15 TABLETS
Storage Guidelines
- Store in a cool, dry place.
- Keep away from direct sunlight and moisture.
User Feedback & Patient Concerns
Patients report effective glucose control, mild weight loss, and improved cardiovascular health when used regularly.
Quick Tips for Oxra 10mg Tablet
- Take at the same time daily.
- Stay hydrated to prevent dehydration.
- Monitor for UTIs and low blood pressure.
Fact Box
- Chemical Class: SGLT2 inhibitors
- Habit Forming: No
- Therapeutic Class: Antidiabetic
- Action Class: SGLT2 inhibitors
Useful Diagnostic Tests
- Fasting Blood Sugar (FBS)
- HbA1c Test
- Renal Function Test (RFT)
More Information & References
- Consult your doctor or refer to the patient leaflet for detailed information.
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/202293s003lbl.pdf
- https://www.medicines.org.uk/emc/product/7607/smpc#gref
- https://www.ema.europa.eu/en/documents/product-information/forxiga-epar-product-information_en.pdf
- https://den8dhaj6zs0e.cloudfront.net/50fd68b9-106b-4550-b5d0-12b045f8b184/0be9cb1b-3b33-41c7-bfc2-04c9f718e442/0be9cb1b-3b33-41c7-bfc2-04c9f718e442_viewable_rendition__v.pdf
- https://www.farxiga-hcp.com/
- https://diabetesjournals.org/care/article/43/Supplement_1/S98/30822/9-Pharmacologic-Approaches-to-Glycemic-Treatment
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/202293s026lbl.pdf
Disclaimer
THE CONTENTS OF THIS WEBSITE ARE FOR INFORMATIONAL PURPOSES ONLY AND ARE NOT INTENDED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE, DIAGNOSIS, TREATMENT, OR PREVENTION OF A DISEASE OR MEDICAL CONDITION. PLEASE CONSULT A PHYSICIAN FOR THE TREATMENT AND/OR MANAGEMENT OF ANY DISEASE OR MEDICAL CONDITION WITHOUT DELAY.